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Transcription factors contribute to the differentiation of cortical neurons, orchestrate specific interneuronal circuits, and define synaptic relationships. Whole-cell, patch-clamp recording in vitro combined with colocalization of molecular cell markers in the adult cortex differentiates distinct interneurons. Interneurons positive for COUP-TFII fired irregular, accommodating and adapting trains of action potentials APs and innervated mostly small dendritic shafts and rarely spines or somata.
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Materials and Methods. Email: peter. Oxford Academic. Google Scholar. Gabor Tamas. Pal Barzo. Szabolcs Olah. Peter Somogyi. Cite Citation. Permissions Icon Permissions. Abstract Transcription factors contribute to the differentiation of cortical neurons, orchestrate specific interneuronal circuits, and define synaptic relationships.
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